Article
Characterization of SARS-CoV-2 intrahost genetic evolution in vaccinated and non-vaccinated patients from the Kenyan population.
Journal of virology - 17 Jun 2025
Lugano Doreen, Mwangi Kennedy, Mware Bernard, Kibet Gilbert, Osiany Shebbar, Kiritu Edward, Dobi Paul, Muli Collins, Njeru Regina, de Oliveira Tulio, Njenga M Kariuki, Routh Andrew, Oyola Samuel O
Abstract excerpt
Vaccination is a key control measure of coronavirus disease 2019 by preventing severe effects of disease outcomes, reducing hospitalization rates and death, and increasing immunity. However, vaccination can affect the evolution and adaptation of SARS-CoV-2 largely through vaccine-induced immune pressure. Here, we investigated intrahost recombination and single nucleotide variations (iSNVs) on the severe acute...
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