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Design of a multi-epitope vaccine against Staphylococcus Aureus lukotoxin ED using in silico approaches

25 Apr 2025

Abstract excerpt

Development of a strategy to combat Staphylococcus aureus is a high priority for the World Health Organization. B cell and helper T lymphocyte (HTL) epitopes of leukotoxin ED (LukED) were predicted using computational tools. The predicted epitopes were screened for conservancy, allergenicity, toxicity, autoreactivity, and population coverage. The immunogenic regions of LukED were linked together and to Human...

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PMID: 40280948
DOI: 10.1038/s41598-025-85147-3

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