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Article

The mutational spectrum of Myocilin gene among familial versus sporadic cases of Juvenile onset open angle glaucoma.

Eye (London, England) - 1 Feb 2021

Gupta Viney, Somarajan Bindu I, Gupta Shikha, Walia Gagandeep Kaur, Singh Abhishek, Sofi Rayees, Chaudhary Richard Sher, Sharma Arundhati

Abstract excerpt

PURPOSE: Juvenile onset primary open angle glaucoma (JOAG) is a rare disorder associated with high IOP and progressive optic neuropathy in patients diagnosed before the age of 40 years. While in some populations it has primarily an autosomal dominant pattern of inheritance, in others it occurs in a primarily sporadic form. The main aim of the study was to assess the relative prevalence of Myocilin (MYOC)...

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Identifiers

PMID: 32300215
DOI: 10.1038/s41433-020-0850-z
PMCID: PMC8027054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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