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Article

CHIP’ing Signal from Noise in Liquid Biopsy

24 Apr 2025

Abstract excerpt

The presence of clonal hematopoiesis in cell-free DNA analysis can distort the interpretation of results and influence cancer treatment decisions. This CCR Translations discusses the importance of distinguishing the origin of cell-free DNA variants as tumoral or hematopoietic and its potential clinical implications. See related article by Magee et al., p. 2710.

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Identifiers

PMID: 40272282
DOI: 10.1158/1078-0432.ccr-25-0569

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