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Metabolic modelling reveals increased autonomy and antagonism in type 2 diabetic gut microbiota

22 Apr 2025

Abstract excerpt

Type 2 diabetes (T2D) presents a global health concern, with evidence highlighting the role of the human gut microbiome in metabolic diseases. This study employs metabolic modelling to elucidate changes in host-microbiome interactions in T2D. Glucose levels, diet, 16S sequences and metadata were collected for 1866 individuals. In addition, microbial community models, and ecological interactions were simulated for...

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PMID: 40263590
DOI: 10.1038/s44320-025-00100-w

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