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Article

Exploring the shared genetic basis of attention-deficit/hyperactivity disorder and obstructive sleep apnea: A multi-omics analysis.

Progress in neuro-psychopharmacology & biological psychiatry - 20 Jun 2025

Huang Yijie, Ju Chao, Luo Jie, Li Yun

Abstract excerpt

BACKGROUND: Observational studies have suggested an association between attention-deficit/hyperactivity disorder (ADHD) and obstructive sleep apnea (OSA), but these findings are often inconsistent due to potential biases from medication use, and varying diagnostic criteria. Genetic analyses can help mitigate these confounding factors, providing additional evidence. METHODS: This study evaluated the genetic...

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Topics

Humans
Attention Deficit Disorder with Hyperactivity
Sleep Apnea, Obstructive
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Polymorphism, Single Nucleotide

Linkage Disequilibrium

Multiomics

Source

Identifiers

PMID: 40246054
DOI: 10.1016/j.pnpbp.2025.111369

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