A multigenerational population-growth assay to capture subtle fitness phenotypes in C. elegans and other nematodes.

Abstract excerpt

Heritable fitness differences between individuals are the currency of evolution but can be challenging to quantify with precision. A slight probabilistic fitness advantage to one relatively healthy individual over another is often too subtle to detect in a single generation. For this reason, we have developed an assay to quantify and compare heritable fitness traits in nematodes by allowing their differences to...

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