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Article

Genetic Association of Primary Angle-Closure Glaucoma and Disease Progression.

Clinical & experimental ophthalmology - 1 Aug 2025

Liang Yu Jing, Ling Anni, Chan Poemen P, Yam Jason C, Pang Chi Pui, Tham Clement C, Chen Li Jia

Abstract excerpt

BACKGROUND: To investigate single-nucleotide polymorphisms (SNPs) reported in the largest up-to-date systematic review and meta-analysis on primary angle-closure disease (PACD), on their associations with primary angle-closure glaucoma (PACG) and disease progression. METHODS: This study involved a case-control design for PACG risk and a case-only design for PACG progression risk, including 628 PACG patients and...

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Source

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Identifiers

PMID: 40234024
DOI: 10.1111/ceo.14539
PMCID: PMC12326230

Genes

ABCA1
LOXL1
VAV3
ABCC5

Variants

rs3825942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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