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Article

Association of Single-Nucleotide Polymorphisms in ABCC5 Gene with Primary Angle Closure Glaucoma and the Ocular Biometric Parameters in a Northern Chinese Population.

Ophthalmic research - 1 Jan 2021

Wang Shaolin, Zhuang Wenjuan, Zhang Wen, Xu Manyun, Li Wenjing, Piao Shunyu, Xue Zhongqi, Cai Bo, Ha Shaoping

Abstract excerpt

BACKGROUND: The rs1401999 gene in ABCC5 gene was the first locus confirmed by a genome-wide association study (GWAS) to be associated with both anterior chamber depth (ACD) and primary angle closure glaucoma (PACG); however, this locus was of obvious heterogeneity among different populations in the GWAS, and the conclusion has not been further verified by other studies. Therefore, this study was carried out to...

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PMID: 32906129
DOI: 10.1159/000511454

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