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Tissue engineered corneal endothelium transplantation in an ex vivo human cornea organ culture model

12 Apr 2025

Abstract excerpt

Transplantation of corneal tissue is the standard treatment for irreversible corneal endothelium decompensation by replacing the malfunctioning corneal endothelial cells and Descemet's membrane. However, this surgery depends on limited donor tissue supply. Thus, developing suitable alternatives for donor grafting material through a tissue engineering approach is needed to enable the transplantation of cultured...

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PMID: 40221533
DOI: 10.1038/s41598-025-96494-6

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