Article
A native-like corneal construct using donor corneal stroma for tissue engineering.
PloS one - 1 Jan 2012
Lin Jing, Yoon Kyung-Chul, Zhang Lili, Su Zhitao, Lu Rong, Ma Ping, De Paiva Cintia S, Pflugfelder Stephen C, Li De-Quan
Abstract excerpt
Tissue engineering holds great promise for corneal transplantation to treat blinding diseases. This study was to explore the use of natural corneal stroma as an optimal substrate to construct a native like corneal equivalent. Human corneal epithelium was cultivated from donor limbal explants on corneal stromal discs prepared by FDA approved Horizon Epikeratome system. The morphology, phenotype, regenerative...
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