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Article

CD73low B-cell phenotypes and distinct cytokine profiles in patients with active anti-Jo-1 antibody positive idiopathic inflammatory myopathies.

RMD open - 9 Apr 2025

Nakazawa Maho, Horuluoglu Begum, de Vries Charlotte, Lodin Karin, Malmström Vivianne, Lundberg Ingrid E, Grönwall Caroline

Abstract excerpt

OBJECTIVES: We performed multiparameter phenotyping of peripheral B cells in anti-Jo-1 antibody positive idiopathic inflammatory myopathies (IIM) to delineate disease-associated immunological profiles and the influence of B cells on disease activity. METHODS: Purified B cells from peripheral blood mononuclear cells from 16 patients with anti-Jo-1 antibody positive IIM (7 with untreated active IIM, 4 with active...

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Identifiers

PMID: 40210261
DOI: 10.1136/rmdopen-2024-005401
PMCID: PMC11987157

Genes

CD19

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