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Article

Association Between Circulating Cytokines and Endometriosis: A Mendelian Randomization Study.

Journal of cellular and molecular medicine - 1 Apr 2025

Xu Xiao, Mei Jie, Zhang Bin, Jiang Xi-Ya, Wang Li, Zhang Ai-Xi, Li Jie-Jie, Chen Shun-Xia, He Yu-Feng, Fang Ya-Xing, Zheng Lan, Jin Qin-Qin, Hu Jing-Jing, Zhou Shu-Guang

Abstract excerpt

Existing evidence shows the importance of circulating cytokines in studying female reproductive system dysfunction. Endometriosis (EM) is thought to be associated with multiple immune cytokines, but its causality has not been proven. Utilising Genome-Wide Association Study (GWAS) data, we performed Mendelian randomisation (MR) to assess causality between 41 cytokines and EM. Positive Single Nucleotide...

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Source

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Identifiers

PMID: 40208252
DOI: 10.1111/jcmm.70532
PMCID: PMC11984317

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TNF

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