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Article

Bidirectional causal relationship between inflammatory cytokines and endometriosis at different sites.

BMC women's health - 9 Dec 2025

Huang Shu-Ping, Zhang Ze-Chao, Ding Wen-Jia, Li Liang-Ying, Li Wei-Hong

Abstract excerpt

OBJECTIVE: This study aims to explore the genetic connection between inflammatory cytokines (IC) and endometriosis (EMs) to provide insights for the treatment of EMs. METHODS: Data from two genome-wide association studies (GWAS) on IC and EMs were analyzed for single nucleotide polymorphisms (SNPs). Both forward and reverse Mendelian randomization (MR) analyses were conducted using inverse variance weighting. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41366411
DOI: 10.1186/s12905-025-04058-7
PMCID: PMC12690902

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