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Article

Causal Effects of Inflammatory Cytokines and Immune Cell Phenotypes on Spontaneous Abortion: Evidence From Mendelian Randomization

1 Mar 2025

Abstract excerpt

Purpose: This study aims to investigate the causal relationship between inflammatory cytokines, immune cells and spontaneous abortion (SA). Methods: A bidirectional two-sample Mendelian randomization (MR) analyses was conducted based on the genetic data of 91 inflammatory cytokines (n=14,824), 731 immune traits (n=3757) and SA (18,680 cases and 162,987 controls) cohorts. Five different MR analysis methods and...

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PMID: 40123752
DOI: 10.2147/ijwh.s501620

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