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Protection against experimental necrotizing enterocolitis by fecal filtrate transfer requires an active donor virome

10 Apr 2025

Abstract excerpt

Necrotizing enterocolitis (NEC) remains a frequent catastrophic disease in preterm infants, and fecal filtrate transfer (FFT) has emerged as a promising prophylactic therapy. This study explored the role of virome viability for the protective effect of FFT. Using ultraviolet (UV) irradiation, we established a viral inactivation protocol and administered FFT, UV-inactivated FFT (iFFT) or sterile saline orally to...

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PMID: 40207909
DOI: 10.1080/19490976.2025.2486517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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