Machine learning combined with multi-omics analysis: identifying nucleotide metabolism-associated immune genes and validating their functions in cardiomyopathy.

Abstract excerpt

BACKGROUND: Cardiomyopathy (CMP) is a heterogeneous group of myocardial disorders with diverse etiologies, posing a significant threat to patient health and quality of life. Accumulating studies have emphasized the role of nucleotide metabolism in CMP pathogenesis, such as regulating myocardial energy homeostasis and inflammatory responses. However, the association between nucleotide metabolism-associated genes...

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