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Article

Identification and immunoassay of biomarkers associated with T cell exhaustion in systemic lupus erythematosus

26 Mar 2025

Abstract excerpt

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with unclear etiology. T cell exhaustion (TEX) suppresses the immune response and can be a potential therapeutic strategy for autoimmune diseases. Therefore, this study primarily investigated the mechanism by which TEX influences SLE, offering a novel target for its treatment. Methods: GSE72326 and GSE81622 were utilized in this study. TEX...

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PMID: 40207215
DOI: 10.3389/fimmu.2025.1476575

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