Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parents facing polygenic embryo scores: the 'best choice of a best life' and psychological counselling.

Human reproduction (Oxford, England) - 1 Jun 2025

Forte Marina, Galliano Daniela, Della Vedova Anna Maria, Pellicer Antonio

Abstract excerpt

Advances in reproductive medicine and genetic technologies now offer prospective parents the option to test IVF embryos for genetic predispositions to complex diseases, such as coronary heart disease and psychiatric disorders, through polygenic embryo screening (PES). However, limited clinical data on its real-world use leaves parents facing complex decisions based on probabilistic risk scores, requiring them to...

Read the complete abstract on PubMed

Topics

Humans
Parents
Preimplantation Diagnosis
Decision Making
Multifactorial Inheritance
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Testing

Genetic Counseling

Genetic Predisposition to Disease

Pregnancy

Source

Identifiers

PMID: 40204628
DOI: 10.1093/humrep/deaf056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parents facing polygenic embryo scores: the 'best choice of a best life' and psychological counselling.PMID 40204628Read ↗

Polygenic Embryo Screening: High Approval Despite Substantial Concerns from the U.S. PublicSemantic proximity Read ↗

Patient Perspectives on Psychiatric Polygenic Risk Scores in Reproductive Decision-Making and Polygenic Embryo Screening.Semantic proximity Read ↗

Divergence Between Clinician and Patient Perspectives on Polygenic Embryo Screening: A Qualitative StudySemantic proximity Read ↗

Polygenic risk scoring of human embryos: a qualitative study of media coverageSemantic proximity Read ↗

“Are we not going too far?“: Socio-ethical considerations of preimplantation genetic testing using polygenic risk scores according to healthcare professionalsSemantic proximity Read ↗

Polygenic Risk Scoring of Human Embryos: a Qualitative Study of Media CoverageSemantic proximity Read ↗

Problems with Using Polygenic Scores to Select Embryos.Semantic proximity Read ↗

Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations.Semantic proximity Read ↗

Capacities and Limitations of Using Polygenic Risk Scores for Reproductive Decision Making.Semantic proximity Read ↗

Concerns about the use of polygenic embryo screening for psychiatric and cognitive traits.Semantic proximity Read ↗

<i>PEStimate</i> : Predicting offspring disease risk after Polygenic Embryo ScreeningSemantic proximity Read ↗

Review of patient decision‐making factors and attitudes regarding preimplantation genetic diagnosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.