Article
Patient Perspectives on Psychiatric Polygenic Risk Scores in Reproductive Decision-Making and Polygenic Embryo Screening.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2026
Ginn Lauren A, Merner Amanda R, Trotter Page M, Craig Kaitlynn P, Martinez Abigail C, Battaglino Ana Lucía, Barlevy Dorit, Ayton Daphne M, Soda Takahiro, Storch Eric A, Lázaro-Muñoz Gabriel, Pereira Stacey
Abstract excerpt
Polygenic risk scores (PRS) estimate individuals' genetic risk for developing multifactorial conditions. Recent genome-wide association studies have enabled development of psychiatric PRS, which hold potential to streamline diagnosis and treatment of psychiatric conditions. As individuals with mental illness often identify concern about passing on psychiatric conditions as a key factor in family planning, some...
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