Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SOX2 commands LIM homeobox transcription factors in choroid plexus development and tumorigenesis

23 Mar 2025

Abstract excerpt

BACKGROUND: Choroid plexus (CP) tumors are rare brain neoplasms that mainly affect the pediatric population. Unlike benign CP papilloma (CPP), CP carcinoma (CPC) is an aggressive cancer with a dismal survival rate. Despite chromosome-wide rearrangements, drivers of most CP tumors remain elusive except recurrent alterations in TP53. Studies of signaling dysregulation may bring biological understanding of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glioma Diagnosis and Treatment
Share to Microtubule and mitosis dynamics
Share to Neurogenesis and neuroplasticity mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40128799
DOI: 10.1093/neuonc/noaf085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SOX2 commands LIM homeobox transcription factors in choroid plexus development and tumorigenesisPMID 40128799Read ↗

An overview of the diagnosis and management of Choroid Plexus tumors.Semantic proximity Read ↗

Choroid plexus papillomas: advances in molecular biology and understanding of tumorigenesisSemantic proximity Read ↗

Correlation between choroid plexus carcinoma and Li-Fraumeni syndrome: implications of TP53 mutations and management strategies-a case-based narrative review.Semantic proximity Read ↗

Epigenetics impacts upon prognosis and clinical management of choroid plexus tumorsSemantic proximity Read ↗

Choroid Plexus Carcinoma in an Adult: Genetic Insights from a Unique Case StudySemantic proximity Read ↗

Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory NeuroblastomaSemantic proximity Read ↗

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroupsSemantic proximity Read ↗

Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesisSemantic proximity Read ↗

Integration of human and mouse single-cell transcriptomes of the developing cerebellum nominates cells-of-origin for Group 3 and 4 medulloblastomaSemantic proximity Read ↗

Single-Cell RNA Sequencing Reveals LEF1-Driven Wnt Pathway Activation as a Shared Oncogenic Program in Hepatoblastoma and MedulloblastomaSemantic proximity Read ↗

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma TumorigenesisSemantic proximity Read ↗

Deconstructing olfactory epithelium developmental pathways in esthesioneuroblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.