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Impact of Aedes aegypti V1016I and F1534C knockdown resistance genotypes on operational interventions

24 Mar 2025

Abstract excerpt

Resistance to pyrethroids is common in Aedes aegypti populations. Mutations in the voltage gated sodium channel have an influence on the insecticide resistance (IR) phenotype. In much of the Western hemisphere, two of these knockdown resistance (kdr) mutations, V1016I and F1534C, result in six kdr genotype combinations in field populations. Strong pyrethroid IR and the failure of permethrin treated uniforms have...

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PMID: 40128542
DOI: 10.1038/s41598-025-94738-z

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