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Article

Retrospective Analysis of BRCA -Altered Uterine Sarcoma Treated With Poly(ADP-ribose) Polymerase Inhibitors

1 Mar 2025

Abstract excerpt

PURPOSE Uterine sarcomas are rare, aggressive tumors with limited chemotherapy responsiveness. Poly(ADP-ribose) polymerase inhibitors (PARPis) have emerged as targeted therapies for patients with BRCA mutations across multiple cancer types, with anecdotal responses in uterine sarcoma. This retrospective, single-center study aims to describe relevant genomic and clinical features of patients with BRCA -altered...

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Share to Endometrial and Cervical Cancer Treatments
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PMID: 40117531
DOI: 10.1200/po-24-00765

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