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First Characterization of HTLV-1 Complete Genomes from Asymptomatic and Symptomatic Argentinean Patients.

AIDS research and human retroviruses - 1 Jun 2025

Pineda María Verónica, Miyazato Paola, Distefano Maximiliano, Tan Jek Yang Benjy, Golemba Marcelo, Bouzas María Belén, Satou Yorifumi, Mangano Andrea

Abstract excerpt

HTLV-1 is the etiologic agent of adult T-cell leukemia/lymphoma (ATL/ATLL) and is related to HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The factors that influence the development of the disease remain unknown. The majority of patients with HTLV-1 infection remain asymptomatic throughout their lives, while 2.5%-5% developed ATLL and 0.3%-2% HAM/TSP. About 10 to 20 million people worldwide...

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Identifiers

PMID: 40103572
DOI: 10.1089/aid.2024.0068

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