Article
Low genetic diversity of the Human T-cell Lymphotropic Virus (HTLV-1) in an endemic area of the Brazilian Amazon basin.
PloS one - 1 Jan 2018
Nobre Akim Felipe Santos, Almeida Danilo de Souza, Ferreira Louise Canto, Ferreira Deimy Lima, Júnior Edivaldo Costa Sousa, Viana Maria de Nazaré do Socorro de Almeida, Silva Ingrid Christiane, Pinheiro Bruna Teles, Ferrari Stephen Francis, Linhares Alexandre da Costa, Ishikawa Edna Aoba, Sousa Rita Catarina Medeiros, de Sousa Maísa Silva
Abstract excerpt
The Human T-cell Lymphotropic Virus (HTLV-1) is a Deltaretrovírus that was first isolated in the 1970s, and associated with Adult T-cell Leucemia-Lymphoma (ATLL), and subsequently to Tropical Spastic Paraparesis-Myelopathy (TSP/HAM). The genetic diversity of the virus varies among geographic regions, although its mutation rate is very low (approximately 1% per thousand years) in comparison with other viruses. The...
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