Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgelin interacts with PARP1 in human colon cancer cells

3 Aug 2020

Abstract excerpt

Abstract Background Transgelin, an actin-binding protein, is associated with cytoskeleton remodeling. Findings from our previous studies demonstrated that transgelin was up-regulated in node-positive colorectal cancer (CRC) versus node-negative disease. Over-expression of TAGLN affected the expression of 256 downstream transcripts and increased the metastatic potential of colon cancer cells in vitro and in vivo....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to PARP inhibition in cancer therapy
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32774160
DOI: 10.1186/s12935-020-01461-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgelin interacts with PARP1 in human colon cancer cellsPMID 32774160Read ↗

Transgelin interacts with PARP1 in human colon cancer cellsSemantic proximity Read ↗

Transgelin interacts with PARP1 and affects Rho signaling pathway in human colon cancer cellsSemantic proximity Read ↗

Transgelins: Cytoskeletal Associated Proteins Implicated in the Metastasis of Colorectal CancerSemantic proximity Read ↗

Transgelins, cytoskeletal proteins implicated in different aspects of cancer developmentSemantic proximity Read ↗

Association of the Actin-Binding Protein Transgelin with Lymph Node Metastasis in Human Colorectal CancerSemantic proximity Read ↗

Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent mannerSemantic proximity Read ↗

Proteomic Profiling of Colon Cancer Tissues: Discovery of New Candidate BiomarkersSemantic proximity Read ↗

TGF-β-induced transgelin promotes bladder cancer metastasis by regulating epithelial-mesenchymal transition and invadopodia formationSemantic proximity Read ↗

Multifaceted role of transgelin isoforms in cancer hallmarksSemantic proximity Read ↗

Transgelin promotes ferroptosis to inhibit the malignant progression of esophageal squamous cell carcinomaSemantic proximity Read ↗

Transgelin-2 is a novel target of KRAS-ERK signaling involved in the development of pancreatic cancer.Semantic proximity Read ↗

Integration of Bulk and Single-Cell RNA-Seq Data to Construct a Prognostic Model of Membrane Tension Related Genes for Colon CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.