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Gelsolin: A comprehensive pan-cancer analysis of potential prognosis, diagnostic, and immune biomarkers

23 Mar 2023

Abstract excerpt

Introduction: Gelsolin (GSN), a calcium-regulated actin-binding protein, is out of balance in various cancers. It can mediate cytoskeletal remodeling and regulate epithelial-mesenchymal conversion (EMT), but the studies on GSN function in pan-cancer are limited. Methods: We studied the transcription level, prognostic impact, diagnostic value, genetic, epigenetic modification, methylation level and immune...

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PMID: 37035750
DOI: 10.3389/fgene.2023.1093163

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