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Article

Intergenerational transmission of polygenic predisposition for neuropsychiatric traits on emotional and behavioural difficulties in childhood.

Nature communications - 18 Mar 2025

Allegrini A G, Hannigan L J, Frach L, Barkhuizen W, Baldwin J R, Andreassen O A, Bragantini D, Hegemann L, Havdahl A, Pingault J-B

Abstract excerpt

Childhood emotional and behavioural difficulties tend to co-occur and often precede diagnosed neuropsychiatric conditions. Identifying shared and specific risk factors for early-life mental health difficulties is therefore essential for prevention strategies. Here, we examine how parental risk factors shape their offspring's emotional and behavioural symptoms (e.g. feelings of anxiety, and restlessness) using...

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Identifiers

PMID: 40102402
DOI: 10.1038/s41467-025-57694-w
PMCID: PMC11920414

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