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Associations between RetNet gene polymorphisms and the efficacy of orthokeratology for myopia control: a retrospective clinical study

17 Mar 2025

Abstract excerpt

BACKGROUND: This study investigated how clinical and genetic factors impact the effectiveness of orthokeratology lenses in myopia. METHODS: A retrospective clinical study was conducted with a sample of 545 children aged 8-12 years who had myopia and have initially worn orthokeratology lenses for one year. Whole-genome sequencing (WGS) was also performed on 60 participants in two groups, one with rapid axial...

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PMID: 40091069
DOI: 10.1186/s40662-025-00426-4

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