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Article

Variant Reclassification in Underrepresented Minority Children With Sensorineural Hearing Loss.

Ear and hearing - 1 Jan 2025

Scaria Sonia M, Harris Jacqueline, Ismail Mohamad Noura, Taketa Emily, Park Yesai, Chan Dylan K

Abstract excerpt

OBJECTIVES: Underrepresented minority (URM, comprising Hispanic, non-Hispanic Black, and Native American) children with sensorineural hearing loss have fivefold lower odds of receiving a genetic diagnosis after undergoing hearing loss gene-panel testing. Using hearing loss-specific American College of Medical Genetics (ACMG)/Association for Molecular Pathology (AMP) guidelines applied to a URM-specific cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40069133
DOI: 10.1097/AUD.0000000000001653

Genes

COL11A2
OTOG
TJP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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