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Article

Bioinformatics exploration of SPHKAP's role in IDH-mutant glioma involving energy metabolism, prognosis, and immune modulation.

Journal of neuroimmunology - 15 May 2025

Liang Xi, Tan Shi, Chen Yuecheng, Wei Cuirong, Qin Zhongqiao

Abstract excerpt

BACKGROUND: The current understanding of glioma pathogenesis is limited by the lack of comprehensive insights into the metabolic reprogramming associated with isocitrate dehydrogenase (IDH) mutations. This study aims to contribute a step to this gap by investigating the role of energy metabolism-related genes in glioma. Our objective is to identify key molecular markers that could serve as prognostic markers and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40058165
DOI: 10.1016/j.jneuroim.2025.578570

Genes

SPHKAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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