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Clinical manifestations, disease penetrance, and treatment in individuals with SOCS1 insufficiency: a registry-based and population-based study

27 Feb 2025

Abstract excerpt

BACKGROUND: Suppressor of cytokine signalling 1 (SOCS1) insufficiency is an inborn error of immunity affecting the negative regulation of cytokine and growth factor signalling. We aimed to enhance the understanding of clinical manifestations, disease trajectories, disease penetrance, and the effect of Janus kinase (JAK) inhibition in individuals with SOCS1 insufficiency. METHODS: This study used data from two...

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Share to Adrenal Hormones and Disorders
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PMID: 40024253
DOI: 10.1016/s2665-9913(24)00348-5

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