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Development of a single-nucleotide polymorphism panel genotyping system for genetic analysis of Chinese hamsters.

Animal models and experimental medicine - 1 May 2025

Sun Minghe, Guo Yafang, Ren Zhengnan, Song Ang, Lu Jing, Li Changlong, Lv Jianyi, Guo Meng, Liu Xin, Du Xiaoyan, Chen Zhaoyang, Song Guohua, He Yan, Chen Zhenwen, Huo Xueyun

Abstract excerpt

Chinese hamster with Chinese characteristics is used in experiments, and it is of great value in the field of medical biology research. However, at present, there is no high-efficiency method for evaluating the genetic quality of Chinese hamsters. Here, we developed a novel Chinese hamster genetic quality detection system using single-nucleotide polymorphism (SNP) markers. To find SNP loci, we conducted whole...

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PMID: 40016881
DOI: 10.1002/ame2.70006
PMCID: PMC12107357

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