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Sex Disparity in Cancer: Role of Autophagy and Estrogen Receptors

13 Feb 2025

Abstract excerpt

Autophagy, a cellular process essential for maintaining homeostasis, plays a fundamental role in recycling damaged components and in adapting to stress. The dysregulation of autophagy is implicated in numerous human diseases, including cancer, where it exhibits a dual role as both a suppressor and a promoter, depending on the context and the stage of tumor development. The significant sex differences observed in...

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PMID: 39996745
DOI: 10.3390/cells14040273

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