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Article

Interacting and joint effects of frailty and inflammation on cardiovascular disease risk and the mediating role of inflammation in middle-aged and elderly populations.

BMC cardiovascular disorders - 20 Feb 2025

Xu Zihan, Wang Yingbai, Li Xiaolin, Hou Xuefei, Yue Suru, Wang Jia, Ye Shicai, Wu Jiayuan

Abstract excerpt

BACKGROUND: Frailty and inflammation may increase the risk of cardiovascular disease (CVD), but their interacting and joint effects on CVDs remain unclear. To explore the interaction effects of frailty and inflammation on CVDs and the role of inflammation in the relationship between frailty and CVDs to provide better understanding of the underlying pathogenesis of CVD. METHODS: A total of 220,608 initially...

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Identifiers

PMID: 39979798
DOI: 10.1186/s12872-025-04567-1
PMCID: PMC11841180

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