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Article

Exploring the causal role of plasma metabolites in pediatric asthma: a Mendelian randomization study.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Dec 2025

Ma Shaojie, Hu Wenjuan, Bi Yingwei, Han Ying, Wang Wei, Xin Deli

Abstract excerpt

BACKGROUND: Pediatric asthma (PA) is the prevailing chronic respiratory ailment in childhood. A better understanding of plasma metabolites is the goal for elucidating the molecular pathological mechanisms of PA and investigating novel therapeutic approaches. METHODS: Data for PA from Genome-Wide Association Studies (GWAS) was derived from the IEU-OpenGWAS project, featuring a collection of 1400 plasma...

Read the complete abstract on PubMed

Topics

Humans
Asthma
Mendelian Randomization Analysis
Child
Genome-Wide Association Study
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Biomarkers

Adolescent

Polymorphism, Single Nucleotide

Child, Preschool

Source

Identifiers

PMID: 40905282
DOI: 10.1080/02770903.2025.2552748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

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