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Article

Performance of homozygosity by descent in two mice lines divergently selected for birth weight environmental variability.

Scientific reports - 14 Feb 2025

Ojeda-Marín Candela, Gutiérrez Juan Pablo, Formoso-Rafferty Nora, Cervantes Isabel

Abstract excerpt

Inbreeding can have negative effects, such as increasing the expression of deleterious alleles or reducing fitness. A method based on Hidden Markov Models (HMM) was developed to determine the probability of an individual genome in a homozygous-by-descent state (HBD). As a result of an experiment of divergent selection for birth weight environmental variability two lines were created: high variability line...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39953099
DOI: 10.1038/s41598-025-89254-z
PMCID: PMC11829033

Genes

HBD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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