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A within-host model on the interactions of sensitive and resistant Helicobacter pylori to antibiotic therapy considering immune response

1 Jan 2025

Abstract excerpt

In this work, we formulated a mathematical model to describe growth, acquisition of bacterial resistance, and immune response for Helicobacter pylori (H. pylori). The qualitative analysis revealed the existence of five equilibrium solutions: (ⅰ) An infection-free state, in which the bacterial population and immune cells are suppressed, (ⅱ) an endemic state only with resistant bacteria without immune cells, (ⅲ) an...

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PMID: 39949168
DOI: 10.3934/mbe.2025009

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