Article
Predictive Computational Modeling of the Mucosal Immune Responses during Helicobacter pylori Infection
5 Sept 2013
Abstract excerpt
T helper (Th) cells play a major role in the immune response and pathology at the gastric mucosa during Helicobacter pylori infection. There is a limited mechanistic understanding regarding the contributions of CD4+ T cell subsets to gastritis development during H. pylori colonization. We used two computational approaches: ordinary differential equation (ODE)-based and agent-based modeling (ABM) to study the...
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