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Article

Arrhythmogenic Potential of Heterozygous TECRL Variants in Type 3 Catecholaminergic Polymorphic Ventricular Tachycardia.

JACC. Clinical electrophysiology - 1 Apr 2025

Porretta Alessandra Pia, Le Bloa Mathieu, Bhuiyan Zahurul Alam, Sekarski Nicole, Atallah Isis, Le Caignec Cédric, Extramiana Fabrice, Pruvot Etienne

Abstract excerpt

TECRL is the causative gene of an autosomal-recessive form of catecholaminergic polymorphic ventricular tachycardia (CPVT), the so-called type 3 CPVT. However, only 17 families have been reported worldwide and no case of symptomatic heterozygous carriers has been described. We report herein genotypes and clinical phenotypes of a family of European ancestry harboring a new TECRL pathogenic variant and, for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39945714
DOI: 10.1016/j.jacep.2024.12.015

Genes

TECRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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Arrhythmogenic Potential of Heterozygous TECRL Variants in Type 3 Catecholaminergic Polymorphic Ventricular Tachycardia.PMID 39945714Read ↗

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