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Article

Novel variants in TECRL cause recessive inherited CPVT type 3 with severe and variable clinical symptoms.

Journal of cardiovascular electrophysiology - 1 Jun 2020

Moscu-Gregor Alexander, Marschall Christoph, Müntjes Carsten, Schönecker Anne, Schuessler-Hahn Franziska, Hohendanner Felix, Parwani Abdul Shokor, Boldt Leif-Hendrik, Ott Claus-Eric, Bennewiz Anja, Paul Thomas, Krause Ulrich, Rost Imma

Abstract excerpt

INTRODUCTION: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by adrenergically stimulated ventricular tachycardia. The most common form of CPVT is due to autosomal dominant variants in the cardiac ryanodine-receptor gene (RYR2). However, trans-2,3-enoyl-CoA reductase-like (TECRL) was recently suggested to be a novel candidate gene for...

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PMID: 32173957
DOI: 10.1111/jce.14446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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