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Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study

11 Feb 2025

Abstract excerpt

Drug-resistant epilepsy (DRE) presents significant challenges in treatment and management. While seizure-related alterations in peripheral immune players are increasingly recognized, the involvement of the immune complement system remains insufficiently explored in DRE. We studied complement components and their relationship to cytokine profiles in serum samples from 46 DRE patients and 45 matched healthy...

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PMID: 39934240
DOI: 10.1038/s41598-025-88654-5

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