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Article

Intracranial Disease Control and Survival among Patients with KRAS-mutant Lung Adenocarcinoma and Brain Metastases Treated with Stereotactic Radiosurgery.

International journal of radiation oncology, biology, physics - 1 Jun 2025

Gaeta Benjamin, Eichholz Jordan E, Walch Henry, Ilica Ahmet T, Boe Lillian, Kratochvil Leah, Yu Yao, Gomez Daniel R, Imber Brandon S, Li Bob T, Murciano-Goroff Yonina R, Arbour Kathryn C, Schultz Nikolaus, Lebow Emily S, Pike Luke R G

Abstract excerpt

PURPOSE: Precision medicine according to molecularly defined subgroups offers great potential to improve outcomes for patients with metastatic lung adenocarcinoma. This study describes clinical outcomes and the impact of co-occurring genetic alterations on outcomes following stereotactic radiosurgery (SRS) among patients with Kirsten rat sarcoma viral oncogene homolog (KRAS)-mutant lung adenocarcinoma. METHODS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39929348
DOI: 10.1016/j.ijrobp.2025.01.033
PMCID: PMC12163228

Genes

KRAS
KEAP1
STK11

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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