Article
Prediction of phenotypes by secretory biomarkers and machine learning in patients with chronic rhinosinusitis.
European review for medical and pharmacological sciences - 1 Jan 2025
Becker M, Kist A M, Wendler O, Pesold V V, Bleier B S, Mueller S K
Abstract excerpt
OBJECTIVE: Chronic rhinosinusitis (CRS) has traditionally been classified phenotypically according to the presence (CRSwNP) or absence (CRSsNP) of nasal polyps. However, the phenotypic dichotomy does not represent the complexity of the disease. Current research thus focuses on identifying underlying inflammatory mechanisms and distinguishing different endotypes. The objectives of this study were 1) to identify...
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