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Article

Current insight into treatment of chronic rhinosinusitis: Phenotypes, endotypes, and implications for targeted therapeutics.

The Journal of allergy and clinical immunology - 1 Jul 2022

Chapurin Nikita, Wu Jeffanie, Labby Alex B, Chandra Rakesh K, Chowdhury Naweed I, Turner Justin H

Abstract excerpt

Chronic rhinosinusitis is characterized by persistent locoregional mucosal inflammation of the paranasal sinuses and upper airway that has substantial associated health care costs. Personalized approaches to care that incorporate use of molecular biomarkers, phenotypes, and inflammatory endotypes is a major focus of research at this time, and the concurrent rise of targeted therapeutics and biologic therapies has...

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Identifiers

PMID: 35469844
DOI: 10.1016/j.jaci.2022.04.013
PMCID: PMC9673979

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