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Characterizing Chemokine Signaling Pathways and Hub Genes in Calcium Oxalate-Induced Kidney Stone Formation: Insights from Rodent Models

1 Feb 2025

Abstract excerpt

The predominant component of kidney stone is calcium oxalate monohydrate (COM), a fact widely acknowledged. Although rodent models are frequently used to induce calcium oxalate (CaOx) crystallization, further exploration of Randall's plaques (RPs) in these models is still needed. We first selected the GSE89028 and GSE75542 datasets from the Gene Expression Omnibus (GEO) database to identify commonly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39893356
DOI: 10.1007/s10528-025-11036-z

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