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Article

Early-Life Exposure to Tobacco Smoke and the Risk of Idiopathic Pulmonary Fibrosis: A Population-Based Cohort Study.

Annals of the American Thoracic Society - 1 Jun 2025

Zhu Jiahao, Wang Yifan, Liu Houpu, Wang Meng, Wang Jing, Ding Lilu, Zhou Dan, Li Yingjun

Abstract excerpt

Rationale: Tobacco smoking is a well-established risk factor for idiopathic pulmonary fibrosis (IPF), yet the influence of early-life tobacco exposure on future IPF risk remains poorly understood. Objectives: We sought to test the hypothesis that early-life tobacco exposure may elevate the risk of developing IPF, with this effect potentially modified by genetic susceptibility to IPF and mediated through...

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PMID: 39879538
DOI: 10.1513/AnnalsATS.202409-906OC

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