Article
Multimodal learning for mapping genotype-phenotype dynamics.
Nature computational science - 1 Apr 2025
Khodaee Farhan, Zandie Rohola, Edelman Elazer R
Abstract excerpt
How complex phenotypes emerge from intricate gene expression patterns is a fundamental question in biology. Integrating high-content genotyping approaches such as single-cell RNA sequencing and advanced learning methods such as language models offers an opportunity for dissecting this complex relationship. Here we present a computational integrated genetics framework designed to analyze and interpret the...
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