Article

Representation learning-based genome-wide association mapping discovers genes underlying complex traits.

2025-09-23

Abstract excerpt

<title>Abstract</title> <p>Genome-wide association studies (GWAS) have provided key insights into the genetic architecture of complex traits. However, traditional approaches fall short in accounting for polygenicity, epistatic interactions, and linkage disequilibrium. We present Representation Learning-Based Association Mapping (RBAM), a framework that leverages variational autoencoders to learn latent genotype e...

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Literature Corpus work: c09a8dae-7ccc-5229-8983-830bd67601b6
DOI: 10.21203/rs.3.rs-7624342/v1

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