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Article

A safe haven for cancer cells: tumor plus stroma control by DYRK1B

25 Jan 2025

Abstract excerpt

The development of resistance remains one of the biggest challenges in clinical cancer patient care and it comprises all treatment modalities from chemotherapy to targeted or immune therapy. In solid malignancies, drug resistance is the result of adaptive processes occurring in cancer cells or the surrounding tumor microenvironment (TME). Future therapy attempts will therefore benefit from targeting both, tumor...

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PMID: 39863750
DOI: 10.1038/s41388-025-03275-6

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